{"id":64006,"date":"2026-06-21T11:06:30","date_gmt":"2026-06-21T10:06:30","guid":{"rendered":"https:\/\/dzwatch.dz\/?p=64006"},"modified":"2026-06-21T11:06:30","modified_gmt":"2026-06-21T10:06:30","slug":"russian-study-early-immune-cell-changes-aging","status":"publish","type":"post","link":"https:\/\/dzwatch.dz\/?p=64006","title":{"rendered":"Russian Study Reveals Early Immune Cell Changes With Aging"},"content":{"rendered":"<p>A recent study by scientists at Sechenov First Moscow State Medical University indicates that the immune system begins to change and gradually decline much earlier in life, between the ages of 30 and 40, rather than solely during old age as previously believed.<\/p>\n<h2>immune system aging<\/h2>\n<p>The research, conducted in collaboration with the Federal Research Institute of Fundamental and Clinical Immunology in Novosibirsk, found that immune cells progressively lose their ability to respond to inflammatory signals. This phenomenon contributes to an increase in chronic inflammation within the body as individuals age, resulting in a paradoxical situation where inflammatory signals intensify while cellular response weakens.<\/p>\n<p>Researchers analyzed blood samples from 144 healthy donors aged 18 to 59. The study focused on examining key inflammatory cytokine receptors present on the surface of immune cells.<\/p>\n<p>Results showed a decrease in certain indicators of immune cell activity and their surface receptors, alongside alterations in other cell types, particularly T-lymphocytes. These findings point to complex changes in the immune system&#39;s response mechanisms as people age.<\/p>\n<p>The scientists believe these findings will enhance the understanding of age-related changes in the immune system. This knowledge could potentially aid in developing personalized therapeutic and preventive strategies to mitigate age-associated diseases and improve their management.<\/p>\n<p><strong>Related topics:<\/strong> immune system, aging, cellular changes, chronic inflammation, age-related diseases, immunology<\/p>\n<p><em>DZWatch provides English-language coverage of Algeria-focused developments for international readers.<\/em><\/p>\n","protected":false},"excerpt":{"rendered":"<p>New Russian research reveals the immune system begins to decline between ages 30-40, not just in old age, impacting chronic inflammation and disease risk.<\/p>\n","protected":false},"author":1,"featured_media":64005,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"rank_math_lock_modified_date":false,"cybocfi_hide_featured_image":"","iawp_total_views":2,"footnotes":""},"categories":[35],"tags":[],"class_list":["post-64006","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-science"],"acf":[],"_links":{"self":[{"href":"https:\/\/dzwatch.dz\/index.php?rest_route=\/wp\/v2\/posts\/64006","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/dzwatch.dz\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/dzwatch.dz\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/dzwatch.dz\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/dzwatch.dz\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=64006"}],"version-history":[{"count":0,"href":"https:\/\/dzwatch.dz\/index.php?rest_route=\/wp\/v2\/posts\/64006\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/dzwatch.dz\/index.php?rest_route=\/wp\/v2\/media\/64005"}],"wp:attachment":[{"href":"https:\/\/dzwatch.dz\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=64006"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/dzwatch.dz\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=64006"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/dzwatch.dz\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=64006"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}